Metchnikoff's policemen: macrophages in development, homeostasis and regeneration
نویسندگان
چکیده
منابع مشابه
Syndecans in skeletal muscle development, regeneration and homeostasis.
Skeletal muscle is a highly dynamic tissue that can change in size in response to physiological demands and undergo successful regeneration even upon extensive injury. A population of resident stem cells, termed satellite cells, accounts for skeletal muscle plasticity, maintenance and regeneration. Mammalian satellite cells, generated from muscle precursor cells during development, are maintain...
متن کاملCell plasticity in homeostasis and regeneration.
Over the past decades, genetic analyses performed in vertebrate and invertebrate organisms deciphered numerous cellular and molecular mechanisms deployed during sexual development and identified genetic circuitries largely shared among bilaterians. In contrast, the functional analysis of the mechanisms that support regenerative processes in species randomly scattered among the animal kingdom, w...
متن کاملMacrophages and systemic iron homeostasis.
As a principal aspect of their scavenging function, splenic and hepatic macrophages phagocytize and degrade senescent and damaged erythrocytes to recover iron, mainly for the production of hemoglobin in new erythrocytes but also for other carriers and enzymes requiring iron. Splenic red pulp macrophages are specialized for iron recycling with increased expression of proteins for the uptake of h...
متن کاملIntestinal Macrophages in Homeostasis and Inflammation
As the intestinal mucosa is continuously exposed to numerous commensal bacteria, it is thought that the gut may possess innate and acquired immune system regulatory mechanisms to prevent excessive inflammatory responses against commensal bacteria. Macrophages are the major population of tissue-resident mononuclear phagocytes, and ISSN 1598-9100 http://dx.doi.org/10.5217/ir.2012.10.4.317 Intest ...
متن کاملMacrophages in intestinal homeostasis and inflammation
The intestine contains the largest pool of macrophages in the body which are essential for maintaining mucosal homeostasis in the face of the microbiota and the constant need for epithelial renewal but are also important components of protective immunity and are involved in the pathology of inflammatory bowel disease (IBD). However, defining the biological roles of intestinal macrophages has be...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Trends in Molecular Medicine
سال: 2011
ISSN: 1471-4914
DOI: 10.1016/j.molmed.2011.07.009